© 2017 Journal of Biomedical Photonics & Engineering. It also suggests that graph-based topological metrics analysis could become a useful method to provide valuable indices of brain function in the evaluation of the LGG. Function reorganization and the rewiring of neuronal circuits allow signal transmission bypassing the lesion area or surgical trauma. Conclusion: To conclude, the present study indicates the existence of compensatory mechanism in LGG patients to adapt to cognitive requirements. By comparing LGG patients preand postoperation, more significantly altered network metrics were obtained from hemisphere network analysis than that from whole-brain network analysis, and network features of dominant hemisphere changed more drastically when the lesion is located in the same hemisphere. Most of hub nodes were identical between LGG and NC groups, while the betweenness centrality values of those hub nodes and some random nodes were higher in the LGG patients. Meanwhile, altered regions in the LGG patients was obtained and various nodal parameters were further calculated in each region. Results: From the graph-based topological metrics of the constructed network, various global parameters changed significantly in LGG patients. The two-factor variance analysis was used to investigate the influence of operation and lesion location on whole-brain and hemisphere networks. Statistical analyses were performed to reveal the significant differences of various network characteristics between LGG patients and NC as well as between LGG patients before and after operation. Brain hub nodes and random nodes between LGG and NC were compared. The structural connections were established by selecting an appropriate connectivity threshold. Method : We constructed whole-brain and hemisphere anatomical networks for 20 LGG patients and 20 normal controls (NC). On this basis, the structural plasticity and function compensatory mechanism of LGG patient were discussed. This study aimed to analyze the topological properties of brain structural networks in LGG patients and investigate the influence of operation and lesion location on whole-brain and hemisphere networks. Purpose: At present, few studies have investigated the functional performance in patients with low grade glioma (LGG) from the perspective of brain structural characteristics. The representations can be projected continuously to an environmental object that we have seen and continue to see, thanks to the mapping from shapes in our memory to shapes in Euclidean space.Аннотация научной статьи по медицинским технологиям, автор научной работы - Tao Ling, Qian Zhiyu, Yang Yamin, Liu Hongyi, Xue Li
High-level representations of objects in our environment are mapped to simplified views (our interpretations) of the objects, in order to construct a symbolic representation of the environment.
#HUMAN BRAIN MAPPING MANUSCRIPT REVISION SERIES#
We show how a series of transformations can be gradually applied to a pattern, in particular to the shape of an object, without affecting its invariant properties, such as boundedness of parts of a visual scene. In particular, we focus on ecological theories of perception, that account for our knowledge of world objects by borrowing a concept of invariance in topology. Here, topological theory of shape provides a mathematical foundation for the notion of persistence perception. During imaginative processes, the same object can be recalled in mind even if it is out of sight. During the exploration of the surrounding environment, the brain links together external inputs, giving rise to perception of a persisting object.
0 kommentar(er)
